Details
Targets of Cancer Diagnosis and Treatment
Ion Transport in Tumor BiologyReviews of Physiology, Biochemistry and Pharmacology, Band 183
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139,09 € |
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| Verlag: | Springer |
| Format: | |
| Veröffentl.: | 05.05.2022 |
| ISBN/EAN: | 9783031039942 |
| Sprache: | englisch |
Dieses eBook enthält ein Wasserzeichen.
Beschreibungen
<p>This third and final volume in the "Ion Transport in Tumor Biology" collection presents novel diagnostic and therapeutic approaches in cancer based on the exploitation of ion transport proteins. The authors critically examine several transportome members, particularly Na<sup>+</sup>, K<sup>+</sup>, Ca<sup>2+</sup>, and Cl<sup>-</sup> channels, as well as organic solute carriers regarding their suitability as therapeutic targets. Synergistic effects resulting from the combined use of classical cytostatics with ion transport-inhibiting drugs are pointed out, and the capability of bispecific antibodies to function as anticancer drugs is discussed. </p><p>As readers will also learn, the use of ion channel inhibitors could improve the outcome of radiotherapy because the development of radio-resistance during radiotherapeutic treatment often correlates with increases in the expression levels and conductance of ion channels. The translational topics of this volume form a bridge between biochemical research and therapeutic application.</p>
As part of a three-volume collection, this book will fascinate members of the active research community, as well as clinicians in the cancer field.
As part of a three-volume collection, this book will fascinate members of the active research community, as well as clinicians in the cancer field.
<p>Targeting Ion Channels for Cancer Treatment: Current Progress and Future Challenges.- Novel Therapeutic Approaches of Ion Channels and Transporters in Cancer.- Ion Channels in Cancer: Orchestrators of Electrical Signaling and Cellular Crosstalk.- Potassium and Chloride Ion Channels in Cancer: A Novel Paradigm for Cancer Therapeutics.- Potassium and Calcium Channel Complexes as Novel Targets for Cancer Research.- Solute Carrier Transportome in Chemotherapy-Induced Adverse Drug Reactions.- Ion Transport and Radioresistance.- Ion Transporting Proteins and Cancer: Progress and Perspectives.</p>
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<b>Targeting Ion Channels for Cancer Treatment: Current Progress and Future Challenges</b><div><i>Alina L. Capatina, Dimitris Lagos, and William J. Brackenbury</i><p></p>
<p><b>Novel Therapeutic Approaches of Ion Channels and Transporters in Cancer</b></p><p><i>Ana Ramírez, Janice García-Quiroz, Luis Aguilar-Eslava, Yesennia Sánchez-Pérez, and Javier Camacho</i></p><p><b>Ion Channels in Cancer: Orchestrators of Electrical Signaling and Cellular Crosstalk</b><br></p>
<p><i>Jerry J. Fan and Xi Huang</i></p>
<p><b>Potassium and Chloride Ion Channels in Cancer: A Novel Paradigm for Cancer Therapeutics</b><br></p>
<p><i>Umberto Banderali, Luigi Leanza, Najmeh Eskandari, and Saverio Gentile</i></p>
<p><b>Potassium and Calcium Channel Complexes as Novel Targets for Cancer Research</b></p>
<p><i>Marie Potier-Cartereau, William Raoul, Gunther Weber, Karine Mahéo, Raphael Rapetti-Mauss, Maxime Gueguinou, Paul Buscaglia, Caroline Goupille, Nelig Le Goux, Souleymane Abdoul-Azize, Thierry Lecomte, Gaëlle Fromont, Aurélie Chantome, Olivier Mignen, Olivier Soriani, and Christophe Vandier</i></p>
<p><b>Solute Carrier Transportome in Chemotherapy-Induced Adverse Drug Reactions</b></p>
<p><i>Jason T. Anderson, Kevin M. Huang, Maryam B. Lustberg, Alex Sparreboom, and Shuiying Hu</i></p>
<p><b>Ion Transport and Radioresistance</b></p>
<p><i>Bastian Roth and Stephan M. Huber</i></p>
<p><b>Ion Transporting Proteins and Cancer: Progress and Perspectives</b></p>
<p><i>Mustafa B. A. Djamgoz</i></p></div>
<p><b>Novel Therapeutic Approaches of Ion Channels and Transporters in Cancer</b></p><p><i>Ana Ramírez, Janice García-Quiroz, Luis Aguilar-Eslava, Yesennia Sánchez-Pérez, and Javier Camacho</i></p><p><b>Ion Channels in Cancer: Orchestrators of Electrical Signaling and Cellular Crosstalk</b><br></p>
<p><i>Jerry J. Fan and Xi Huang</i></p>
<p><b>Potassium and Chloride Ion Channels in Cancer: A Novel Paradigm for Cancer Therapeutics</b><br></p>
<p><i>Umberto Banderali, Luigi Leanza, Najmeh Eskandari, and Saverio Gentile</i></p>
<p><b>Potassium and Calcium Channel Complexes as Novel Targets for Cancer Research</b></p>
<p><i>Marie Potier-Cartereau, William Raoul, Gunther Weber, Karine Mahéo, Raphael Rapetti-Mauss, Maxime Gueguinou, Paul Buscaglia, Caroline Goupille, Nelig Le Goux, Souleymane Abdoul-Azize, Thierry Lecomte, Gaëlle Fromont, Aurélie Chantome, Olivier Mignen, Olivier Soriani, and Christophe Vandier</i></p>
<p><b>Solute Carrier Transportome in Chemotherapy-Induced Adverse Drug Reactions</b></p>
<p><i>Jason T. Anderson, Kevin M. Huang, Maryam B. Lustberg, Alex Sparreboom, and Shuiying Hu</i></p>
<p><b>Ion Transport and Radioresistance</b></p>
<p><i>Bastian Roth and Stephan M. Huber</i></p>
<p><b>Ion Transporting Proteins and Cancer: Progress and Perspectives</b></p>
<p><i>Mustafa B. A. Djamgoz</i></p></div>
Demonstrates how ion channels and transporters could be used as tumor markers Provides novel transport-focused approaches in anti-cancer treatment Opens up new perspectives in treatment strategies for cancer
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