Details
Helicobacter pylori in Human Diseases
Advances in Microbiology, Infectious Diseases and Public Health Volume 11Advances in Experimental Medicine and Biology, Band 1149
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149,79 € |
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| Verlag: | Springer |
| Format: | |
| Veröffentl.: | 22.10.2019 |
| ISBN/EAN: | 9783030219161 |
| Sprache: | englisch |
Dieses eBook enthält ein Wasserzeichen.
Beschreibungen
<p>This book gathers a wealth of contributions on the virulence factors and pathogenic mechanism of <i>Helicobacter pylori</i>, prepared by leading international experts. In addition, it explores the epidemiology, diagnosis, treatment with drugs and probiotics, and prophylaxis by vaccination, reflecting the latest advances. </p>
<p><i>H. pylori</i> is a Gram negative microaerophilic bacterium that can produce various gastric diseases including gastritis, gastroduodenal ulceration, gastric cancer and gastric MALT lymphoma. Although efforts to combat <i>H. pylori</i> using a combination of proton pump inhibitor and several antimicrobial drugs have significantly decreased the burden of these gastric diseases, the microbial epidemiology and gastric pathogenesis following <i>H. pylori</i> infection are still not fully understood.</p>
<p>Given its scope, the book offers a valuable resource not only for basic microbiologists, but also for researchers in the fields of pathology, biochemistry and genomics, as well as medical students/scientists. <br></p><br>
<p><i>H. pylori</i> is a Gram negative microaerophilic bacterium that can produce various gastric diseases including gastritis, gastroduodenal ulceration, gastric cancer and gastric MALT lymphoma. Although efforts to combat <i>H. pylori</i> using a combination of proton pump inhibitor and several antimicrobial drugs have significantly decreased the burden of these gastric diseases, the microbial epidemiology and gastric pathogenesis following <i>H. pylori</i> infection are still not fully understood.</p>
<p>Given its scope, the book offers a valuable resource not only for basic microbiologists, but also for researchers in the fields of pathology, biochemistry and genomics, as well as medical students/scientists. <br></p><br>
From the contents: 1. Genomic diversity of <i>Helicobacter pylori</i> and human migrations.- 2. Epidemiology, diagnosis and risk factors of <i>Helicobacter pylori</i> infections.- 3. Activities and functional importance of <i>Helicobacter pylori</i> virulence factors.- 4. Structural and functional aspects of the <i>Helicobacter pylori</i> proteome.- 5. Role of adhesion to epithelial cells in gastric colonization by <i>H. pylori</i>.- 6. Interplay of <i>Helicobacter pylori</i> with immune cells: impact on gastric pathology.- 7. <i>Helicobacter pylori</i> infection of children.- 8. Non-malignant <i>Helicobacter pylori</i>-associated diseases.- 9. Malignant <i>Helicobacter pylori</i>-associated diseases: gastric cancer and MALT lymphoma.- 10. Host genetic polymorphisms in gastric disease outcome.- 11. <i>Helicobacter pylori</i> genetic polymorphisms in gastric disease development.- 12. Crosstalk of <i>Helicobacter pylori </i>withthe gastrointestinal microbiota.- 13. Treatment of <i>Helicobacter pylori</i> infection.- 14. Role of probiotics in eradication therapy for <i>Helicobacter pylori</i> infection.- 15. Immunity and vaccine development against <i>Helicobacter pylori.</i>
<p></p><p>Shigeru Kamiya (Kyorin University, Japan)</p><p></p><p>Steffen Backert (Friedrich-Alexander University Erlangen, Germany<b>)</b></p><div><br></div><p><br></p>
<p>This book gathers a wealth of contributions on the virulence factors and pathogenic mechanism of <i>Helicobacter pylori</i>, prepared by leading international experts. In addition, it explores the epidemiology, diagnosis, treatment with drugs and probiotics, and prophylaxis by vaccination, reflecting the latest advances. </p><p><i>H. pylori</i> is a Gram negative microaerophilic bacterium that can produce various gastric diseases including gastritis, gastroduodenal ulceration, gastric cancer and gastric MALT lymphoma. Although efforts to combat <i>H. pylori</i> using a combination of proton pump inhibitor and several antimicrobial drugs have significantly decreased the burden of these gastric diseases, the microbial epidemiology and gastric pathogenesis following <i>H. pylori</i> infection are still not fully understood.</p><p>Given its scope, the book offers a valuable resource not only for basic microbiologists, but also for researchers in the fields of pathology, biochemistry and genomics, as well as medical students/scientists. <br></p><div><br></div>
Reviews the virulence factors and pathogenic mechanisms of H. pylori Assesses microbial epidemiology and gastric pathogenesis following H. pylori infections Offers a wealth of valuable insights for microbiologists and medical scientists alike
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